It has been unfolded by the recent study on mice that Candida Albicans – a harmless fungus – is a cause of many memory and brain disorders and resembles the characteristics of Alzheimer’s disease. Alzheimer’s is the most common type of dementia which includes memory loss and cognitive decline. Here we will talk all about “candida infection symptoms” – Memory problems
Candida albicans is the most common yeast that we live with. It instinctively grows in human respiratory tunnel, opening, and vagina. It is one of the species of fungus. Even if yeast is not harmful, still it can be a cause of thrush and many other severe infectious germs that troubles the blood vessels and other body tissues. The most prevailing source of mycological infectious germs in bodies and the fungal pathogens that affect people is Candida albicans. The types of candida albicans infection include urinary yeast infection, genital yeast infection, oral thrush, and mucocutaneous candidiasis. The taster chosen from the affected or malicious area will be used to identify the organism from what species it belongs to. Mostly this particular disease is treated by the antifungal medication. Nature Communications- a journal- contains the recent study that stacked up to the body parts and it is about C. albicans. A Contemporary research on mice revealed that fungal attacks may affect the brain functioning, activate a seditious rejoinder, and enfeeble memory.
The entry of candida albicans in our bloodstreams can be originated as severe contagions in other body parts as well other than blood itself;
- Neutropenia- a dangerous factor occurs when the number of cells which are known as neutrophils get abnormally low leveled. People with cancer mostly experience this particular disorder.
- Candidemia- is like an infection caused within the blood with the support of special species called candida species. It can be caused by several risk factors like spectrum used for use for antibiotics and other kinds of surgery. Its most common symptoms are high temperature, kidney diseases, and shock.
- Endocarditis- an infection in the heart’s inner linings which includes hearts compartments and controllers. Deteriorated immunity, heart’s disorders, prolonged antibiotics usage, and cardiovascular surgeries contribute to its risk factors. Fever, cough, difficult breathing and body pain are its common symptoms.
Associative study of C. albicans and Brain
Several things are interconnected like fungi with respiratory infections and then with dementia which is explained by Dr. Corry serves as the motivation for research. Dr. Corry maintained that fungi were the cause of many upper side allergic infections like asthma. According to him, it can also give rise to other symptoms like one of them is sepsis. Sepsis is a deadly disease triggered by the body’s reaction to an infection. It occurs when the bacterial infection reaches the blood and the strong reaction by the immune system can cause organ failure. It is one of the fatal diseases which is most difficult to identify as its symptoms are very tricky to be pointed out and can be mistaken for other serious illnesses. Sepsis along with other infections that are caused by fungus have associated with a difficult and dangerous complexities of dementia, the fact highlighted by Dr. Corry.
Impact of C. albicans on the brain and its memory unit
Many dosages of C. albicans were tested by Dr. Corry and his co-workers on a model composed of infectious rats. All they were striving was to ascertain a certain amount that may seem appropriate to distress the brain but not such as to produce the crippling disease. Ultimately, the experts made a decision to vaccinate total 25,000 yeast dosage in the rodent’s bloodstream. The whole tea shocked by astounding results that fungal cells breached the barrier that was drawn in between the blood brain. The brain is protected from the pathogens that may happen in the bloodstreams by the blood-brain barrier. It separates the brain’s ducts or blood vessels or veins from cells and tissues. However, the person name who crossed the sensitive and delicate barrier is C. albicans and affected the immune cells of the brain. Dr. Corry thought that the yeast couldn’t penetrate into the brain, but in actual it happened. The yeast actually sparked the microglia activity (an immune cell). The cells were so active in consummating or and assimilating the yeast and they generated a he number of molecules that moderated the inflammatory response which in turn capture the disease inside the brain’s structure look like granule. This structure was later called by researchers as fungus which produced FIGG which is pronounced as fungus-induced glial granuloma. It was also observed by the researchers the formation of FIGGs led to the development of a special type of protein named as amyloid precursor and some molecules of special kind of protein known as amyloid beta which are developed within the yeast cells.
Resemblances with Alzheimer’s disease
Alzheimer’s disease is characterized by special kind of protein known as amyloid precursor protein and another one amyloid beta protein which may generate a yellowish material or something like plaque within the brain. The researchers compared the diseased rats with the unaffected ones while testing the mice’s memory. RSM possessed by the infected mice, but once the contamination was vacant the mice’s spatial memory got recovered. All these researches show that the part occupied by fungi in humanoid infection hypothetically deals with allergic diseases (asthma) or sepsis. The results made the scientists vigilant to deliberate the probability that in some scenarios fungi is seemed to be active in the production of neurodegenerative disorders, such as, Alzheimer’s, Parkinson’s and numerous sclerosis. The scientists are contemporarily exploring the possibility. In the view of Dr. Corry, by developing the understanding about how the human internal system goes with that type of invariable and constant, and by knowing the faintness in our immune system that takes place with the passage of time and keeping track of fungous infections produce and reproduce, only in that case people can find the ways forward to come back with enough caliber of fighting against the illness.